Episode 011 Cover Art

EP011 - Diabetes Dirty Dozen - Part 10

June 16, 20256 min read

Gut Dysbiosis and Type 2 Diabetes: How to Build a Happy, Healthy Gut

“Leaky gut is like a slow drip—stuff that should stay in your gut leaks into your blood and drives chronic inflammation.”

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Type 2 diabetes is driven by insulin resistance, but one big piece starts in your gut. Today we’re talking about gut dysbiosis—an imbalance in the bugs that live in your belly.

Your gut is home to trillions of tiny helpers called microbes. They are not just along for the ride. They help you digest food, protect you from germs, and keep your metabolism working. When they’re in balance, they help lower inflammation, improve insulin sensitivity, and keep your gut lining strong.

What a Healthy Gut Looks Like

  • Your gut microbes help digest fiber and make short-chain fatty acids (SCFAs): butyrate, acetate, and propionate.

  • SCFAs lower inflammation, improve insulin sensitivity, and protect your gut lining.

  • Helpful bacteria like Akkermansia muciniphila and Roseburia intestinalis support GLP-1 (a hormone that helps your body release insulin and slow stomach emptying).

  • A strong gut lining keeps junk out of your blood. That means less inflammation and better blood sugar control.

What Is Gut Dysbiosis?

  • Gut dysbiosis means the good and bad bacteria are out of balance.

  • When the gut lining gets “leaky,” toxins like LPS (lipopolysaccharides) can slip into your blood.

  • This can cause chronic inflammation.

  • Chronic inflammation blocks insulin signaling and raises insulin resistance.

  • Dysbiosis can lower GLP-1, push your body to store more fat, and make blood sugar control harder.

  • Over time, it can affect kidneys, nerves, and blood vessels.

Leaky Gut: Slow Trouble vs. Fast Trouble

Richie: A burst gut is an emergency. Leaky gut is a slow drip. It won’t send you to the ER today, but over years it can cause big problems.

Amber: Exactly. It’s not sudden, but chronic inflammation from gut dysbiosis can still harm your health over time.

Medications and Gut Dysbiosis

  • Metformin: We used to think it worked mainly in the liver and muscles. Newer research shows it may also help balance gut bacteria. Some people get stomach side effects with metformin, even though it may help the microbiome.

  • GLP-1 receptor agonists: These mimic the hormone that gut dysbiosis can reduce. They help with insulin release and slow stomach emptying.

  • Antibiotics: These are “scorched earth.” They can wipe out both helpful and harmful bacteria. Use only when needed.

Are There Tests?

  • Some stool (fecal) tests can measure gut bacteria, but they’re not common for everyday use.

  • Fecal microbiota transplants (FMT) can help certain gut problems like severe infections or IBS in some cases, but that’s a medical treatment, not a daily tool for diabetes.

Who Are the “Good Guys” in Your Gut?

  • 90% of your gut bacteria come from two big families: Firmicutes and Bacteroidetes.

  • People with more Bacteroidetes often have less insulin resistance.

  • But it’s not just one family vs. the other. What matters most is the right species and overall diversity.

How to Feed the Good Guys: Simple Food Wins

Think of your gut like a garden. What you feed it decides what grows.

Build Your Gut Barrier and Lower Inflammation

  • Goal: Support Akkermansia muciniphila (helps your gut lining and insulin sensitivity)

  • Eat polyphenol-rich foods:

    • Cranberries

    • Pomegranate

    • Red/purple grapes

    • Green tea

  • Add inulin-rich prebiotics:

    • Garlic

    • Onions

    • Leeks

    • Asparagus

    • Artichokes

Make More Butyrate (SCFAs) for Insulin Sensitivity

  • Goal: Support Roseburia intestinalis (a key butyrate producer)

  • Eat resistant starch and beta-glucans:

    • Green bananas (very little to no yellow)

    • Potatoes and sweet potatoes

    • Old-fashioned or steel-cut oats

    • Barley

Boost Diversity with Fermented Foods

  • Goal: Support Lactobacillus species (reduce inflammation and improve diversity)

    • Sauerkraut and kimchi (L. plantarum)

    • Kefir and plain yogurt (watch added sugar) (L. casei)

    • Sourdough bread (L. fermentum)

    • Some traditionally fermented olives (if available)

Calm the Immune System

Goal: Support Bacteroides fragilis (makes polysaccharide A to balance the immune system)

  • Eat a diverse plant-based mix:

    • Beans and lentils

    • Many colors of fruits and veggies

    • Whole grains beyond just wheat (try farro, barley, quinoa)

  • Add omega-3 rich foods:

    • Chia seeds

    • Flax seeds

    • Walnuts

  • More polyphenols:

    • Blueberries

    • Red/purple grapes

    • Cocoa powder (unsweetened/dark)

It’s Not Just “More Fiber.” It’s the Right Fiber + Polyphenols.

  • Different fibers feed different microbes.

  • Polyphenols (the colorful plant compounds) also feed helpful gut bacteria.

  • SCFAs made by these bacteria help “heal” your gut lining and improve insulin sensitivity.

Make It Easy: Healthy Gut Bingo

We made a simple tool to help you add variety over a week. Think “dietary bingo.” Try to hit new squares each week, not the same one over and over.

  • Aim for 30 different plant foods each week.

  • Mix fruits, veggies, beans, seeds, nuts, whole grains, herbs, and fermented foods.

  • Add 1 more new food each week than last week.

Daily Habit Checklist

  • Eat plants at every meal

  • Include a fermented food (small serving)

  • Pick a polyphenol drink or food (green tea, berries, cocoa)

  • Add a resistant starch or beta-glucan (oats, barley, potatoes, green banana)

  • Use prebiotic veggies (onion, garlic, leeks, asparagus, artichokes)

  • Move your body daily (walks count!)

Quick Q&A

  • Do I need supplements? Maybe, but food-first is safer. Overdoing one probiotic strain can backfire.

  • Do I need to test my microbiome? Not usually. Start with food diversity and habits.

  • Is dark chocolate okay? Choose unsweetened cocoa powder or very dark chocolate with low sugar.

  • What yogurt should I pick? Plain, low or no added sugar; look for live and active cultures.

Bring It Home

Eat more plants. Eat a variety. Include fermented foods. Add berries, beans, dark leafy greens, and whole grains. Move daily. Your gut helps your blood sugar more than you think.

Want help getting started? Grab the Healthy Gut Bingo and try to beat your weekly score!

Final Thought

Gut dysbiosis can push insulin resistance. A healthy, diverse gut can pull you back toward better blood sugar, less inflammation, and a stronger gut barrier. Small steps, every week, add up.

Need Support?
Got questions? Email [email protected].

Disclaimer

The information in this blog post and podcast is for educational and informational purposes only. It is not medical advice, diagnosis, or treatment, and it does not replace a one-on-one relationship with your physician or qualified healthcare professional. Always talk with your doctor, pharmacist, or care team before starting, stopping, or changing any medication, supplement, exercise plan, or nutrition plan—especially if you have diabetes, prediabetes, heart, liver, or kidney conditions, or take prescription drugs like metformin or insulin.

Results vary from person to person. Examples, statistics, or studies are shared to educate, not to promise outcomes. Any discussion of medications, dosing, or side effects is general in nature and may not be appropriate for your specific situation. Do not ignore professional medical advice or delay seeking it because of something you read or heard here. If you think you are experiencing an emergency or severe side effects (such as persistent vomiting, severe diarrhea, signs of dehydration, allergic reaction, or symptoms of lactic acidosis), call your local emergency number or seek urgent care right away.

We strive for accuracy, but health information changes over time. We make no guarantees regarding completeness, timeliness, or suitability of the content and assume no liability for actions taken or not taken based on this material. Use of this content is at your own risk.

Links or references to third-party resources are provided for convenience and do not constitute endorsement. By reading, listening, or using this information, you agree to these terms and understand that you are responsible for your own health decisions in partnership with your licensed healthcare provider.

Empowered Diabetes presents The Diabetes Podcast providing real talk about Type 2 diabetes, prediabetes, and the path to remission. Hear expert insights and practical strategies to lower blood sugar, regain energy, and reduce or eliminate medications—so you can thrive, not just survive

Empowered Diabetes

Empowered Diabetes presents The Diabetes Podcast providing real talk about Type 2 diabetes, prediabetes, and the path to remission. Hear expert insights and practical strategies to lower blood sugar, regain energy, and reduce or eliminate medications—so you can thrive, not just survive

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